thallium poisoning timeline

"[48] arrow-right-small-blue [10], There are a variety of common chelating agents with differing affinities for different metals, physical characteristics, and biological mechanism of action. c.74[1] [4] A document from the United States Department of State confirms that the project aimed to "help Cuba overthrow the Communist regime", including its leader Fidel Castro, and it aimed "for a revolt which can take place in Cuba by October 1962". The Po-210 used to poison Mr Litvinenko was made at the Avangard facility in Sarov, Russia. [47], Many assassination ideas were floated by the CIA during Operation Mongoose. Conflicting accounts in the Inspector General's report of how later events during this time period played out make it difficult to discern the path of how the Cuba task force handled its operations. Various other methods of assassination that had been thought of by the CIA included exploding seashells, having a former lover slip him poison pills,[56] and exposing him to various other poisoned items such as a fountain pen and even ice cream. [47] Another key interest for Operation Mongoose was the Cuban refugees as it was thought they wanted to overthrow the Communist regime in Havana and recapture their homeland. "[33], During the planning of "OPERATION MONGOOSE" a March 1962 CIA Memorandum sought a brief, but precise description of pretexts which the Joint Chiefs of Staff considered would provide justification for American military intervention in Cuba. The last possibility was to use a provocation and overthrow the Castro-Communist regime by U.S. military force. As predicted, Blofeld attended his funeral in Rome and, realizing that she is a liability, arranged a failed attempt on the life of Sciarra's widow, Lucia Sciarra. Thallium initial hypothesis Amit Nathwani, one of Litvinenko's physicians, said "His symptoms are slightly odd for thallium poisoning, and the chemical levels of thallium we were able to detect are not the kind of levels you'd see in toxicity." 2016;31(8):970. doi:10.1007/s11606-016-3628-z. 962 3147. Am J Clin Dermatol. [59], Besides Litvinenko, only two people left polonium trails: Lugovoy and Kovtun, who were school friends and worked previously for Russian intelligence in the KGB and the GRU, respectively. By 1962 it was shown that other nations were funding Castro's revolution.[42]. "[4], According to the findings of a 1997 systematic review, EDTA chelation therapy is not effective as a treatment for coronary artery disease and this use is not approved in the United States by the US Food and Drug Administration (FDA).[37]. On 3 December, reports stated that Britain had demanded the right to speak to at least five Russians implicated in Litvinenko's death, and Russian Foreign Minister Sergey Lavrov asserted that Moscow was willing to answer "concrete questions. Oxygen toxicity is a condition resulting from the harmful effects of breathing molecular oxygen (O 2) at increased partial pressures.Severe cases can result in cell damage and death, with effects most often seen in the central nervous system, lungs, and eyes.Historically, the central nervous system condition was called the Paul Bert effect, and the pulmonary condition the Lorrain [7] At least some of the CIA assassination attempts on Castro were given the CIA project name ZRRIFLE. Operation Mongoose consisted of a program of covert action, including sabotage, psychological warfare, intelligence collection, and the creation of an internal revolution against the communist government. The wounded Blofeld crawled from the wreckage and was confronted by 007. They had a trade embargo, denial of bunkering facilities, increased port security, and control procedure on transshipment, technical data, and customs inspection. Exposure to them should not exceed 0.1 mg per m 2 of skin in an 8 hour time "[65] Russian Prosecutor-General Yuri Chaika said on Tuesday 5 December that any Russian citizen who may be charged in the poisoning will be tried in Russia, not Britain. Only two MSRs have ever operated, both research reactors in the United States.The 1950's Aircraft Reactor Experiment was primarily motivated by the compact size that the technique offers, while the 1960's Molten-Salt Reactor From Le Chiffre's encounter with Bond in the original Casino Royale novel in 1953 to Lyutsifer Safin's scheme in the 2021 film, No Time To Die, Bond's foes have been one of the most important reasons for the book and film series' continued popularity. The design for a machine to lay rail track, the "Trac Rail Transposer", is patented and goes on to be used by, Became the first country in the world to deploy an approved COVID-19 vaccine, Heavily involved in the development of the, First person to person to publicly predict and describe (although not the inventor) of the, Modified version of the Newcomen steam engine (Pickard engine) , The first industrially practical screw-cutting lathe , Development of the world's first commercially successful manufacture of high quality flat glass using the, First correct description of circulation of the, First blood pressure measurement and first cardiac catheterisation-, The first scientist to demonstrate that a, First baby genetically selected to be free of a, Ambulight PDT: light-emitting sticking plaster used in photodynamic therapy (PDT) for treating non-melanoma skin cancer. Each month since his presentation, a different method was in place to destabilize the communist regime. The CIA began to worry that their involvement with the anti-Castro movement would lead to an anti-US movement. [29][30] Mario Scaramella, who had eaten with Litvinenko at Itsu, reported that doctors had told him the body had five times the lethal dose of polonium-210. Lawrence: University of Kansas Press, 2008. A congenital form of the disease can The Special Group provided plans on March 14, 1962, for the first phase of the operation until the end of July 1962. Deceased; accidentally poisoned with Heracles by James Bond, which was arranged by Lyutsifer Safin Priest asserts that "whoever did it was probably not an expert in radiation protection, so they probably didn't realize how much contamination you can get just by opening the top (of the vial) and closing it again. [43] As Phase 1 drew to a close Phase II projected plan was written up and considered four possibilities. According to Noam Chomsky, it had a budget of $50 million per year, employing 2,500 people including about 500 Americans, and remained secret for 14 years, from 1961 to 1975. [69][70][71] Russian authorities later said that Britain has not handed over any evidence against Lugovoy. Thallium poisoning can cause damage to multiple organs, especially to the liver, kidneys, and heart. [85][86] The Court's findings were consistent with those of the UK inquiry; it ruled that it was "beyond reasonable doubt that the assassination had been carried out by" Andrey Lugovoy and Dmitry Kovtun; that there was "prima facie evidence of state involvement" and that there was a "strong" case that the two assassins were acting as agents of the Russian State; and that Russia had failed to investigate the murder or to identify and punish those responsible. The top secret document which revealed the plan, which was never put into practice, was one of 2,800 related to the federal investigation of the Kennedy assassination, which were released as scheduled in October 2017. [42] Additionally, the trial was criticized for lacking prior Phase I and II studies, and critics summarized previous controlled trials as having "found no evidence that chelation is superior to placebo for treatment of CAD or PVD. J Gen Intern Med. He left radioactive traces again in his hotel prior to meeting Litvinenko at the hotel's tearoom, but did not administer the poison, perhaps due to security cameras in the room. In February, Lansdale offered a comprehensive review of all Operation Mongoose activities to date. [32][33][18] The symptoms seen in Litvinenko appeared consistent with an administered activity of approximately 2GBq (50mCi) which corresponds to about 10micrograms of 210Po. In other cases, the white nail plate may remain permanently or demonstrate recurrence. Character information [49], A 2011 declassified CIA volume titled "Air Operations, March 1960April 1961" from the comprehensive "Official History of the Bay of Pigs Operation," made the indication that "it was clear from the outset that air operations would play a key role in the CIA program to oust the Cuban leader." Police would not confirm details of the shooting or of the condition of Joyal. It was officially authorized on November 30, 1961 by US President John F. Kennedy.The name Operation Mongoose had been agreed at a prior White House meeting on November 4, [53] Parents either have a doctor use a treatment for lead poisoning, or buy unregulated supplements, in particular DMSA and lipoic acid. DMPS has experimental status in the United States, while ALA is a common nutritional supplement. He believed that time was of the essence, especially given intensified Soviet military build-up in Cuba. Chelation therapy is the preferred medical treatment for metal poisoning, including acute mercury, iron (including in cases of sickle-cell disease and thalassemia), arsenic, lead, uranium, plutonium and other forms of toxic metal poisoning. This would likely involve further probes by the CIA into Cuba. 111202002, 247508004, 247510002, 73751008, 403297002, 763792009, 50458000, 74102009, 47139007, 403302004, 403304003, True leukonychia: discolouration due to abnormal nail plate. An FBI spokesman said the agency was "assisting" the police investigation into the shooting. ", "Spy writers say Litvinenko case stranger than fiction", "Restaurant Polonium: In Sheffield klingeln die Kassen", "Business booming at Polonium restaurant in English city, manager says", "Polonium Name Drives Customers to Restaurant", "Hunting the KGB Killers gripping documentary more outrageous than a spy movie", https://en.wikipedia.org/w/index.php?title=Poisoning_of_Alexander_Litvinenko&oldid=1121085398, November 2006 events in the United Kingdom, Poisoning by drugs, medicaments and biological substances, European Court of Human Rights cases involving Russia, Article 2 of Protocol No. True leukonychia: partial or whole nail plate damage caused by injury to the nail plate or matrix. DermNet does not provide an online consultation service. However, Eduard Limonov observed that the same argument was raised after the assassination of Anna Politkovskaya, and described Litvinenko's death as "very public execution. It showed that although roughly only a quarter of the Cuban population stood behind the Castro regime, the rest of the population was both disaffected and passive. [44] The mafioso John Roselli was introduced to the CIA by former FBI Agent Robert Mahue. Verona requested US$10,000 in expenses and US$1,000 worth of communications equipment. [7] In September 2021, the European Court of Human Rights (ECHR) ruled that Russia was responsible for the assassination of Litvinenko and ordered Russia to pay Litvinenko's wife 100,000 in damages plus 22,500 in costs. The Cuban Project, also known as Operation Mongoose, was an extensive campaign of terrorist attacks against civilians and covert operations carried out by the U.S. Central Intelligence Agency in Cuba. It proceeds to state, "The desired resultant from the execution of this plan would be to place the United States in the apparent position of suffering defensible grievances from a rash and irresponsible government of Cuba and to develop an international image of a Cuban threat to peace in the Western Hemisphere. The final product, however, was solid botulin pills that would dissolve in liquid. Apparent leukonychia: secondary to disease of the nail bed. Oldest publisher and printer in the world (having been operating continuously since 1584): first book printed in English: "The Recuyell of the Historyes of Troye" by Englishman, Symbol for "is less than" and "is greater than" , Discovery of the "White Spot" on Saturn Will Hay, Important contributions to the development of, Proposes the law of octaves, a precursor to the, Publishes Opus Maius, which among other things, proposes an early form of the, Publishes several Aristotelian commentaries, an early framework for the, World's first underground railway and the first, Whirling speculum, This device can be seen as a precursor to the, The world's first patent for an underwater echo ranging device (, Devising the diagramatic system of representing. Hepatotoxicity has been reported with products containing Reynoutria multiflora (synonym Polygonum multiflorum), glycyrrhizin, Senecio and Symphytum. [9] Giancana recommended Orta as being an official in the Cuban government, who had access to Castro. 2022;23(2):17793. [8] The declassified documents did not reveal if Roselli, Giancana or Trafficante accepted a down payment for the job. Official History of the Bay of Pigs 1 (1961): 303506. [28][101][102][103] This of course does not exclude the possibility that the polonium that killed Litvinenko was imported by a licensed commercial distributor, but no oneincluding the Russian governmenthas proposed that this is likely, particularly in regard to the radiation detected on the British Airways passenger jets travelling between Moscow and London. Executive Order No. [53], When it became clear that Litvinenko had been poisoned by a radioactive substance, a team of scientists were assembled to investigate how far the contamination had spread; traces of polonium-210 were subsequently found at more than 40 locations in and out of London. The season consists of 20 episodes and aired on Thursdays at 8:00 pm (ET). Blofeld had also taken the time to confirm to Bond that Max Denbigh did indeed work for SPECTRE, and that his Nine Eyes scheme would allow SPECTRE to have access to all the world's intelligence gathering systems. hierdurch ist es immer in unserem Wertschtzung, Ihnen nur Gute und werthaltige Produkte zu [19] Scaramella, attached to the Mitrokhin Commission investigating KGB penetration of Italian politics, claimed to have information on the death of Anna Politkovskaya, 48, a journalist who was killed at her Moscow apartment in October 2006. In the fall of 1963, Desmond Fitzgerald, a high-ranking official once under the tutelage of Frank Wisner and a good friend of future CIA Director William Colby, who had served in CIA stations across the Far East during the 1950s, pursued Cubela's clandestine services. As the pain intensified, Litvinenko asked his wife to call an ambulance,[23] before being hospitalized on 3 November. It is a heavy metal that is denser than most common materials. The black-shouldered kite (Elanus axillaris) is a small raptor found in open habitat throughout Australia. [21] A month after the failure of the Bay of Pigs Invasion, the CIA proposed a program of sabotage and terrorist attacks against civilian and military targets in Cuba. In the Oliver Stone film JFK, Operation Mongoose is portrayed in flashback sequences as a training ground where, among others, Lee Harvey Oswald becomes versed in anti-Castro militia tactics. Abdullah Shah: killed at least 20 travelers on the road from Kabul to Jalalabad while serving under warlord Zardad Khan; also killed his wife; executed in 2004.; Argentina. Weight [26] In 2010 the U.S. Food and Drug Administration (FDA) warned companies who sold over-the-counter (OTC) chelation products and stated that such "products are unapproved drugs and devices and that it is a violation of federal law to make unproven claims about these products. Blofeld had little self-preservation instinct, despite his vile character. Ozgundogdu, Feyza Cakir. SPECTRE, Independent In the long run, we would be able to work on eliminating Castro at our leisure and from a good vantage point. "[46] Critics of the study characterized the study as showing no support for the use of chelation therapy in coronary heart disease, particularly the claims to reduce the need for coronary artery bypass grafting (CABG, pronounced "cabbage"). Some common chelating agents are ethylenediaminetetraacetic acid (EDTA), 2,3-dimercaptopropanesulfonic acid (DMPS), and thiamine tetrahydrofurfuryl disulfide (TTFD). As the months of 1962 went by, Verona constructed a team of three men to strike at Castro; however, the plans were canceled twice with the Inspector General's report citing conditions inside then the October missile crisis threw plans awry. Later that evening, Blofeld chaired a rare meeting of the organisation at the Palazzo Cardenza; during which Mr. Hinx was chosen as Sciarra's replacement, with the brutal killing of Guerra. Brown A week later, on 6 April, Skripal was said to no longer be in a critical state. This appearance disappears with pressure application on the nail. The United Kingdom Government COBRA committee met to discuss the investigation. The New Illustrated Medical and Health Encyclopedia. The conclusion Harvey drew to this is that the three militia never did leave for Cuba. Muehrcke lines: A pair of observable, non-, Lindsay nails (half-and-half nails): Proximally white or pink-coloured nail with a, Described as small white spots on the nails. Many individual plans were devised by the CIA to assassinate Castro. Blofeld is visited in prison by James Bond. This was at the peak of the Cuban Missile Crisis, wherein the U.S. and the USSR came alarmingly close to nuclear war over the presence of Soviet missiles in Cuba, verified by low flying aircraft on photographic missions and ground surveillance photography. Poisoning is a non-violent way to kill someone. Tends to be the result of trauma and isolated to a few nails. "[73] The effort to mend the relationships would be framed heavily by the negative relations formed due to Operation Mongoose. Home Office pathologist Dr Nicholas Hunt could not entirely exclude that someone else had been involved but declared wounds were self-inflicted and a cause of death as haemorrhaging. "[6], In 1998, the U.S. Federal Trade Commission (FTC) charged that the web site of the American College for Advancement in Medicine (ACAM) and a brochure they published had made false or unsubstantiated claims. "Boys' Brigade want alumni to return for a special anniversary". There were four main objectives for Phase 1; a. was to gather hard intelligence on the target area, b. A person familiar with the case said he was in critical condition in hospital. The worst accidental mass poisoning from carbon monoxide was the Balvano train disaster which occurred on 3 March 1944 in Italy, when a freight train with many illegal passengers stalled in a tunnel, leading to the death of over 500 people.. Over 50 people are suspected to have died from smoke inhalation as a result of the Branch Davidian Massacre during the Waco siege in [18], Just days later on April 16, there were initially 11 targets that were scheduled to be attacked. Other allegations included involvement of rogue FSB members[120] or suggestions that Litvinenko was killed because of his research of certain Russian corporations or state officials,[121][122] or as a political intrigue to undermine president Putin. The first plan in this time frame involved an attack on the radio station Castro used to broadcast his speeches with an aerosol spray of a chemical that produced reactions similar to those of lysergic acid (LSD). A key form of documentation used to construct the timeline of plots was oral testimony collected years after the plots were originally planned. Medical uses. "[9], Alexander Litvinenko was a former officer of the Russian Federal Security Service (FSB) who escaped prosecution in Russia and received political asylum in the United Kingdom. This phase may then be followed by seizures, slow heart rate, low blood pressure, loss of consciousness, and cardiac arrest. As some documents released by the National Security Archive reveal, this happened fairly soon after the project ended. Dawn Sturgess and her partner, Charlie Rowley, were also accidentally exposed to the Novichok poison, which lead to Dawn Sturgess' death. This list covers innovation and invention in the mechanical, electronic, and industrial fields, as well as medicine, military devices and theory, artistic and scientific discovery and innovation, and ideas in religion and ethics. [9]:175176 In November 1961, Robert Kennedy and Richard Goodwin suggested to President Kennedy that the U.S. government begin this campaign, and it was authorized by the President. CIA covert operations and intelligence gathering station JM/WAVE in Miami was established as the operations center for Task Force W, the CIA's unit dedicated to Operation Mongoose. At this stage, it was still not clear that these efforts would end up leading to the Bay of Pigs invasion.[24]. Convicted serial killers by country Afghanistan. Congenital: familial leukonychia is more commonly inherited recessively, although dominant patterns are possible. Now the sole remaining member of the organisation, Blofeld came under the scrutiny of SIS, who confiscated his prosthetic eye and permitted Bond to perform an interrogation. Somehow, Blofeld survived the conflagration, but was left severely scarred on the right side of his face and blind in his right eye. Treatment ultimately depends on the presence of any underlying cause. Traces left by Kovtun were found in Hamburg, Germany. [3][6] Litvinenko's allegations about misdeeds of the FSB and his public deathbed accusations that Putin was behind his poisoning resulted in worldwide media coverage. 11,905, 3 C.F.R. In the chaos, Bond escaped and shots a fuel line, causing the entire complex to be consumed in an enormous fireball. Some scholars saw this plan-of-attack as a "carrot and stick" approach of Kennedy in dealing with Castro. [6], Chelation therapy is the preferred medical treatment for metal poisoning,[1][7] including acute mercury, iron (including in cases of sickle-cell disease and thalassemia),[8][9] arsenic, lead, uranium, plutonium and other forms of toxic metal poisoning. The anti-Castro movement would lead to an anti-US movement may then be followed by seizures, heart. An official in the Cuban government, who had access to Castro would likely involve further probes by National. Said he was in place to destabilize the communist regime ] Giancana recommended Orta as being an official in chaos. Last possibility was to gather hard intelligence on the target area, b for 1! Main objectives for Phase 1 ; a. was to gather hard intelligence the... Close Phase II projected plan was written up and considered four possibilities [ 69 ] 71... 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