centaur Created Date: 9/18/2014 10:03:45 AM . Long-term use of paracetamol in high doses can lead to damage to the liver and kidneys.A large number of medicines used simultaneously, alcoholism, alcoholic liver damage, sepsis or diabetes mellitus can increase the risk of hepatotoxicity of paracetamol in therapeutic doses. CNS depression is accompanied by impaired respiration and cardiovascular function (decreased heart rate, decreased blood pressure before vascular insufficiency). Before using the drug, you need to consult a doctor: In case of renal failure, the doctor should assess the risk / benefit ratio before starting to use the drug. ((U=UJXM_*2M66xOwUO{RnBgljOHD8sCGA m#@Iy/k Travelers are permitted to bring a two-month (60 day) supply of any permissible over-the-counter medication, and an equivalent amount of vitamins. Treatment with activated charcoal should be considered if an excessive dose of paracetamol was taken within 1 hour. Read about company. The maximum daily dose of this product is 10 caplets (3,250 mg acetaminophen) in 24 hours. endobj Centaur Tablet Tablet 20 mg Usage, Dosage, Side Effects Check more here: Centaur Tablet 20 mg is an antidiabetic drug that is used alone or in combination with other drugs to treat type 2 diabetes, a disease that attacks adults causing high blood sugar. Zv}F [fBrG|K]NEeyhm Zf.V!Rh4gTMCE{9a06DcN;@e As for Paracetamol, each one contains 500 mg and adults can take 2 tablets up to four times a day. Do not use simultaneously with MAO inhibitors and within 2 weeks after discontinuation of MAO inhibitors; with tricyclic antidepressants, -adrenergic blockers. T chlorpheniramine maleate is 8 hours. If so, take it as soon as you remember; but when its time for your next dose, skip it and take it on your normal schedule. If you suspect an overdose, consult a doctor immediately. Cetirizine is a hydroxyzine derivative and a second-generation H1 Histamine blocker (antihistamine drug). QNoWUu7Isy6[0P1+!S>^ ZNiZ~[\*9J&X+/0xJn2[[deELrY <=1@sz[)Jm{uGS(oLlARk,O4VrZ ?5K%T97;-,#4uRG97hxYE:T,iX# mX yUwuDg3c=v~x?2lL@wKw8&I3(W}EbcOaYK5fpwj"m[("P]kW endobj Only logged in customers who have purchased this product may leave a review. An overdose caused by the action of phenylephrine and chlorpheniramine maleate can cause sweating, psychomotor agitation or depression of the central nervous system, headache, dizziness, drowsiness, impaired consciousness, heart rhythm disturbance, tachycardia, extrasystole, tremors, hyperreflexia, cramps, nausea, nausea, anxiety, increased blood pressure. x[s}k$MGX3NE)()_o AO& Centaur tablets 20 mg are effective in lowering the amount of glucose released by the liver. Do not exceed the dose prescribed by your doctor. Brand Name : Brexocold Tablet Composition: Paracetamol 500mg; Phenylephrine HCL 5mg; Caffeine 30mg; Diphennhydramine Hydrochloride; Packing Type : 10*10 Tab %PDF-1.5 In rare cases, after an overdose of paracetamol, ARF with acute tubular necrosis has been reported, which can manifest severe pain in the lower back, hematuria, proteinuria and develop even in the absence of severe liver damage; nephrotoxicity (renal colic, interstitial nephritis, papillary necrosis). Paracetamol . endobj Paracetamol may affect laboratory test results for blood glucose and uric acid levels. Binding to blood proteins is less than 10%. QUICK LINKS: Side effects Concerns Usage Side effects Major & minor side effects for Sinarest Tablet Nausea or Vomiting if the symptoms do not disappear and / or are accompanied by high body temperature, which lasts more than 3 days; paracetamol absorption rate may increase with simultaneous use with metoclopramide and domperidone, decrease with cholestyramine; elimination of antibiotics from the body may be slowed; barbiturates and alcohol can enhance the hepato- and nephrotoxicity of acetaminophen, barbiturates reduce the antipyretic effect; anticonvulsants (phenytoin, barbiturates, carbamazepine), isoniazid and rifampicin may enhance the hepatotoxic effect of paracetamol; tetracycline increases the risk of anemia and methemoglobinemia caused by paracetamol; the effect of indirect anticoagulants may increase with an increased risk of bleeding with prolonged regular use of paracetamol; may decrease the effectiveness of diuretics; antacids and food reduce the absorption of paracetamol. endobj 5 0 obj A single dose for adults and children from 12 years old 1 package. 80 Countries where we ship to 3 0 obj Take medication at the time and dose specified. It has anti-allergic effect, eliminates rhinorrhea, lacrimation and itching in the eyes and nose. Antiflu (CONTRACT PHARMACAL CORPORATION, USA). Paracetamol is analgesic and antipyretic chemically it is N - (4- hydroxyphenyl) acetamide. Save my name, email, and website in this browser for the next time I comment. MLAC[LWGi(G/yu~1?,xAG\P$A}OV}Gj*YG@9{svQi5f%Okr\~@/M_7=f JEWWgq-mnp,jd/>SnX(IdY}S""E|;DXN4Xep7Z42esqB>JeyL[=\e00e#n[1|wk_Wm{bp_jm=zON&i+9\kB)[N}}V endobj If skin redness, rashes, blisters, or peeling occur, discontinue use of paracetamol and seek medical attention immediately. endobj Qualitative and Quantitative composition . The common cold is a respiratory illness affecting the nose and throat, mostly caused by viruses known as 'rhinovirus'. endstream The mean retention times of phenylephrine, paracetamol, caffeine and chlorpheniramine were found to be 1.8, 3.1, 5.2 and 10.9 . AstraZeneta entered Phase I clinically in the study of COVID-19 antibody cocktail therapy. =vnj/Xr/L;{z ^>;P1h}2Hc)y$dN!s,9BV>NoO"T@gkIxR Xo 7m'Qoo"&"ei>MR_XfC%z"7=BKfm,VmCItXN|zdz Use during pregnancy and lactation. the presence of chronic malnutrition and dehydration; mild to moderate hepatic insufficiency (9 points on the Child-Pugh scale); thyroid diseases, except hyperthyroidism, which is indicated in the CONTRAINDICATIONS section; glaucoma, except for angle-closure glaucoma, which is indicated in the CONTRAINDICATIONS section. Cytostatic effects can be reduced by administering methionine orally or by administering cysteamine or N-acetylcysteine for 8 hours after an overdose. Add to cart Add to Wishlist Compare Category: Musculoskeletal system The information given here relates to the salt content of the drug. In patients with severe infections, such as sepsis, accompanied by a decrease in glutathione, taking paracetamol may increase the risk of metabolic acidosis (see OVERDOSAGE). The maximum daily dose 4 packets per day should not be exceeded. (Eve): ibuprofen tablets. The most common are usually mild and can include: Nausea, rash, redness of the skin, allergic reactions, shortness of breath, nausea, tinnitus, dry mouth, dry mouth, decreased appetite, anemia, thrush, stomach problems, heartbeat, dizziness, stomach discomfort. Your email address will not be published. more than 4,000 mg of acetaminophen in 24 hours; with other drugs containing acetaminophen; 3 or more alcoholic drinks every day while using this product (We`ll never share your email address with a third-party.). xZ]o}$m$-\4>%URv;3A.E [3g}cg+}_)RvyN Q%ego{m(Wo~0>4G7?C u"s8[Zvbnm/~2>\emo`W",;ThcOh W +~H{ The "Eve A" version is suitable for colds and flu. Paracetamol, Phenylephrine, Chlorpheniramine (Tablets) SKU: 17614 In Stock Phenylephrine hydrochloride is an -adrenergic agonist, which, due to the vasoconstrictor action, reduces swelling and hyperemia of the mucous membrane of the upper respiratory tract and sinuses. It is used to ease allergy signs. The maximum dose for children is up to 100 mg / kg / day, or 4000 mg / day. The patient should be immediately taken to the clinic, even if there are no early symptoms of an overdose. % The drug is not recommended to be used simultaneously with sedative, hypnotics or drugs containing alcohol, due to the increased risk of hepatotoxicity. It is used to ease pain and fever. With prolonged use in high doses, aplastic anemia, pancytopenia, agranulocytosis, neutropenia, leukopenia, thrombocytopenia are possible. with the daily use of analgesics for mild arthritis. Zg32.PS''KptYx7h. Levocetirizine is an antihistamine that reduces the effects of natural chemical histamine in the body. <> Composition:- Aceclofenac IP 100 mg, Paracetamol IP 325 mg, Cetirizine Hcl IP 10 mg, Phenylephrine Hcl 5 mg & Caffeine Anhydrous IP 25mg Tablet Colour : Sunset Yellow Use:- paracetamol which is a pain reliever (analgesic) and helps reduce your temperature when you have a fever phenylephrine which is a decongestant to reduce swelling in the passages of the nose to help you breathe more easily . It also reduces your appetite and increases your bodys sensitivity to insulin, thereby reducing the amount of glucose absorbed into your blood. endobj <> With simultaneous use with paracetamol, the following types of interactions may occur: With the simultaneous use of paracetamol with hepatotoxic drugs, the toxic effect of drugs on the liver increases. *We have emerged as one of the leading manufacturers and suppliers of Paracetamol, Phenylephrine HCL,Caffeine & Diphenhdramine Hcl Tablets. <>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 594.96 841.68] /Contents 4 0 R/Group<>/Tabs/S>> Symptomatic treatment of influenza, acute respiratory viral infections and colds in order to reduce body temperature, eliminate headaches, pain in muscles and joints, swelling of the mucous membrane of the respiratory tract. The therapeutic effect develops within 1 hour after oral administration and lasts for 24 hours. It also decreases your appetite and increases your body's sensitivity to insulin, thus, reducing the amount of glucose that is absorbed by your blood. 8 0 obj (Both paracetamol and tylenol are the same thing.) Sinarest Tablet is a combination medicine which may be used to relieve nasal congestion, excess production of mucus, runny nose, headache, fever, etc. Chlorpheniramine maleate is an antihistamine in the class of alkyl amines, blocker H1histamine receptors. If, on the recommendation of a doctor, the drug is used for a long period, it is necessary to monitor the functional state of the liver and the picture of peripheral blood. 2 0 obj Is it dangerous to use it for food and wine? To decrease the sensation of roughness when a tablet, which is rapidly disintegrated by saliva (rapidly disintegrating tablet), is orally taken, we prepared rapidly disintegrating tablets using microcrystalline cellulose (Avicel PH-M series), a new type of pharmaceutical excipient that is spherical and has a very small particle size (particle size, 7-32 microm), instead of conventional . Prolonged use of paracetamol, especially in combination with other analgesics, can lead to irreversible damage to the kidneys and the risk of kidney failure (analgesic nephropathy). 9 0 obj Clinical signs of liver damage may not occur within 1248 hours after an overdose. Frequent clinical manifestations that occur after 3-5 days include jaundice, fever, hemorrhagic diathesis, hypoglycemia, hepatic breath, liver failure. Uses Of Paracetamol, Phenylephrine, Diphenhydramine HCL & Caffeine Tablets The combination of 4 supplements provides comfort to the person by curing the symptoms of the common cold including fever, cough, runny nose, watery eyes, stuffy nose, congestion, etc. Swallow the tablet whole as soon as you remove the tablet from the strip. <> <> Trumac Healthcare is an ISO 9001:2015, WHO:GMP, GLP Certified Pharma Company in Chandigarh offering more than 2000+ high quality Medical Products. The simultaneous use of ergot alkaloids (ergotamine, methysergide) increases the risk of ergotism. 1 0 obj <>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>> <> Hypersensitivity to the components of the drug; on the part of the blood system: anemia, sulfhemoglobinemia and methemoglobinemia (cyanosis, shortness of breath, heart pain), thrombocytosis, thrombocytopenia, leukopenia, agranulocytosis, hemolytic anemia, bruising or bleeding; from the digestive tract: heartburn, nausea, vomiting, dry mouth, discomfort and pain in the epigastrium, hypersalivation, decreased appetite, constipation, diarrhea, flatulence; on the part of the hepatobiliary system: impaired liver function, increased activity of liver enzymes, usually without the development of jaundice; hepatonecrosis (dose-dependent effect); from the endocrine system: hypoglycemia up to hypoglycemic coma; from the immune system: hypersensitivity reactions (including allergic reactions), anaphylactic reactions and anaphylactic shock; from the nervous system: headache, weakness, dizziness, psychomotor agitation and disorientation, anxiety, fear, sleep disorders, drowsiness, insomnia, dyskinesia, behavior change, irritability or nervousness, tremor, confusion, depression, tingling sensations and heaviness in the limbs, tinnitus, epileptic seizures, coma; from the urinary system: renal colic and interstitial nephritis, urinary retention and difficulty urinating, aseptic pyuria; on the part of the organ of vision: impaired vision and accommodation, dry eyes, mydriasis; on the part of the skin and subcutaneous tissues: itching, rash on the skin and mucous membranes (usually a generalized rash, erythema, urticaria), allergic and angioedema, acute generalized exanthematous pustulosis, local drug-induced dermatitis, erythema multiforme (including Stevens syndrome toxic epidermal necrolysis (Lyell syndrome), including death; from the cardiovascular system: tachycardia, reflex bradycardia, shortness of breath, heart pain, increased blood pressure, arrhythmia; with prolonged use in high doses, myocardial dystrophy is possible; from the respiratory system: bronchospasm in patients sensitive to acetylsalicylic acid and other NSAIDs. Women should stop breastfeeding while taking the drug. Disorders of glucose metabolism, hypokalemia and metabolic acidosis (including lactic acidosis), increased activity of hepatic transaminases and an increase in prothrombin index, hemorrhage can occur. Excretion is significantly impaired with impaired renal excretory function, which can lead to the accumulation of paracetamol and its metabolic products in the body. Hypersensitivity to insulin also lowers cholesterol and helps with weight loss. j;:hCg(X!8=L^B* endobj Increased sensitivity to insulin also lowers your levels of cholesterol and helps you to lose weight. More than 6500 brands Antidepressants, antiparkinsonian and antipsychotic drugs, phenothiazine derivatives increase the risk of urinary retention, dry mouth, and constipation. ltd) containing 15 . 2 0 obj endobj The effectiveness of the antidote decreases sharply after this time. 4 0 obj This product contains acetaminophen. Centaur Tablets are mainly prescribed for the treatment of colds and fevers and at the same time help relieve earaches, allergies, headaches, fevers, colds, joint pains, itchy throat or skin, toothaches, etc. The medicine contains paracetamol, which, due to hepatotoxicity, cannot be used longer and at doses higher than recommended in the APPLICATION section. 7 0 obj The risk of overdose occurs in patients with non-cirrhotic alcoholic liver disease. the mechanism of its action is to inhibit the synthesis of prostaglandins and affect the center of thermoregulation in the hypothalamus. which doesn't represent ECHEMI's opinion. 110 Tablets / 10x1x10 Tablets / 1010 Tablets / 25x1x4 Tablets: Available strength: 500mg + 5mg + 2mg: Therapeutic use: Anticold: If you need more than two months' supply, a Yakkan Shomei () would then be needed. Dont forget take a dose. It increases in individuals with liver disease. In case of an overdose, symptomatic therapy is necessary, with severe hypertension the use of -adrenergic blockers. (Tylenol): paracetamol tablets. endobj The source of this page with content of products and services is from Internet, %PDF-1.5 Simultaneous use of Antiflu with the following medicines can significantly increase the inhibitory effect of chlorpheniramine maleate: Chlorpheniramine enhances the anticholinergic effect of atropine, antispasmodics, tricyclic antidepressants, antiparkinsonian drugs. if the patient uses warfarin or similar drugs that have an anticoagulant effect; if the patient has breathing problems, chronic lung disease, emphysema or chronic bronchitis; a patient with liver disease or infectious liver lesions, such as viral hepatitis; a patient with kidney disease, as a dose adjustment may be required. . stream In most cases, the drug is well tolerated. Levocetirizine is used to treat symptoms of year-round (perennial) allergies in adults and children who are at least 6 months old. % In order to provide you a personalized shopping experience, our site uses cookies. What do I need to tell my doctor BEFORE I take Acetaminophen, Chlorpheniramine, and Phenylephrine Tablets? Symptoms may be limited by nausea and vomiting, or may not reflect the severity of an overdose or the risk of organ damage. Do not use in children under 12 years of age. Drug use and effects may vary from person to person. 10. MP Scholarship Portal 2.0 Online Registration, E-KYC Status, Namo Tablet Yojana Registration Online Namo E-Tablet Apply Here, Karnataka Nekar Samman Yojana 2022 Apply Online, Check Eligibility, WB Snehaloy Housing Scheme Apply Online, Eligibility, PM Atal Vayo Abhyudaya Yojana 2022 Apply Online, Benifits. It is generally well tolerated when taken according to the prescribed dosage instructions. Centaur tablets 20 mg are effective in lowering the amount of glucose released by the liver. <>>> ^_ju0cQ]tjxAGG5!{sY9Q0E[lEf TDO_w>z4zJQ#kjM}4"T%h Warning for sugar and sucrose: if the patient is intolerant of certain sugars, consult your doctor before taking this medication; the drug may be harmful to the teeth. The simultaneous use of phenylephrine with digoxin and cardiac glycosides can lead to an increased risk of heart failure or heart attack. CETIRIZINE+PARACETAMOL+PHENYLEPHRINE belongs to a category of 'cough and cold medications' primarily used to treat the common cold and allergic symptoms like sneezing, watery eyes or itchy/watery nose and throat. Dosage form and strength Oral suspension containing Paracetamol 250 mg, Phenylephrine 5 mg, Chlorpheniramine . With an overdose of chlorpheniramine maleate, atropine-like symptoms can be observed: mydriasis, photophobia, dry skin and mucous membrane, fever, intestinal atony. Here chlorpheniramine maleate blocks the effects of the bodys own histamine and thus reduces the negative symptoms caused by histamine. Each SINAREST Tablet contains: Paracetamol IP 500 mg Phenylephrine hydrochloride IP 10 mg . It is rapidly distributed in tissues. Phenylephrine may decrease the effectiveness of -adrenergic receptor blockers and other antihypertensive drugs (e.g., debrisoquine, guanethidine, reserpine, methyldopa). The impression of spring plowing behind the hard-to-sell fertilizer, The difference between PU and NC wood paint Seven differences to look at carefully. Pain relief drugs (recommended for those age 15 and over): (Chintzu zai): for headaches or toothache, menstrual pain, and fever. With the help of this tablet, you will be increased activity of hormones that help maintain blood sugar levels before or after meals. Reduced by administering methionine orally or by administering cysteamine or N-acetylcysteine for 8 hours an! 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